Ask what your sequences could do

From sequence to
biological function.

Which proteins could explain a biological process? Upload a genome or proteome, predict candidate functions, and explore the evidence behind each annotation.

Start with your sequences

One analysis runs at a time. Larger genomes may take several minutes. Use public or non-sensitive sequences; this service has no account-based access control.

Follow the biological evidence

Find candidate functionsDeepGO++ Light combines sequence similarity with evidence from a precomputed protein association network. Prediction runs on your uploaded sequences.
Apply biological contextGSPA integrates the predictions using the selected organism context. Inspect the supporting sources and any changes to the annotations.
Investigate a biological questionSearch a process such as “threonine biosynthesis”, find candidate proteins, and inspect their genomic neighbours when coordinates are available.

A predicted function is a hypothesis. Scores help prioritise candidates; they do not establish experimental function or prove pathway completeness. Proteins without a close homolog may receive no prediction.

Predictions below 0.5 are omitted. This CPU service uses DeepGO++ Light (sequence and network evidence). It does not run the full GPU model, InterProScan, or external genome-quality tools.

From sequence tobiological function.

Your analysis

Start with your sequences

From sequence to
biological function.